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Dr. Reyzelman Curriculum Vitae

Alexander M. Reyzelman, D.P.M., F.A.C.F.A.S.

California School of Podiatric Medicine
2299 Post St. Ste. 205
San Francisco, California 94115
(415) 292-0638
(415) 292-0718 fax
Email: areyzelman@samuelmerritt.edu

Education

1991-1995
California College of Podiatric Medicine

San Francisco, CA

Doctor of Podiatric Medicine

1987-1991
University of San Francisco

San Francisco, CA

Bachelor of Science in Biology

Post Graduate Training

1995-1996

Primary Podiatric Medical Residency

1996-1998

Podiatric Surgical Residency

University of Texas Health Science Center at San Antonio

2004

Intensive course in peripheral nerve surgery

Work Experience

1998 to present

Private practice

San Francisco, CA

Castro Valley, CA

1999 to 2001

Clinical Director, Pacific Coast Wound Care

San Francisco, CA

2000 to 2001

Private practice

Co-chair Department of Medicine, California College of Podiatric Medicine

San Francisco, CA

09/2001-2009

Clinical Director, Pacific Coast Wound Care

San Francisco, CA

2000 to 2001

Assistant Professor, Chairman, Department of Medicine

California School of Podiatric Medicine at Samuel Merritt College

07/2009-present

Associate Professor, Dept of Medicine

California School of Podiatric Medicine at Samuel Merritt University.

09/2011-present

Co-Director, UCSF Center for Limb Preservation

Clinical Instructor, Dept of Orthopedic Surgery and Dept of Surgery

VASF-Podiatry Dept.

Hospital Staff Appointments

2011 to present

VASF

San Francisco, CA

2011 to Present

UCSF Medical Center

San Francisco, CA

1999 to Present

California Pacific Medical Center

San Francisco, CA

1999 to Present

Eden Hospital

Castro Valley, CA

2008 to Present

St. Mary’s Hospital

San Francisco, CA

1999 to 2007

Mercy San Juan Hospital

Carmichael, CA

1995 to 1998

University Hospital (Residency)

San Antonio, Tx

1995 to 1998

Audie L. Murphy Veterans Administration

Hospital (Residency)

San Antonio, Tx

Licensure

1996-98

Texas

1998 to Present

California

2005 to Present

Nevada

Certification

2005 to Present

Board Certified in Foot Surgery

1995 to 1999

Advanced Cardiac Life Support

1995 to Present

Basic Life Support

1998 to Present

QME, AME

Professional Affiliations

1995 to Present

American Podiatric Medical Association

1998 to Present

California Podiatric Medical Association

1995 to 1998

Texas Podiatric Medical Association

1995 to Present

American College of Foot and Ankle Surgeons

1995 to Present

American Diabetes Association

Lectures and Workshops

1995 to 1996

Peripheral nerve injuries UTHSC-SA

Tendon injury and surgery UTHSC-SA

Radiographic analysis of a bunion UTHSC-SA

1996 to 1997

Differential diagnosis of lower extremity edema.

Bandera Hill Country Seminar, Bandera, Texas

Diabetic footwear post amputation
Vascular surgery grand rounds

Implant arthroplasty of the great toe joint UTHSC-SA

Klippel Trenuanay Syndrome
Podiatry grand rounds

1997 to 1998

Foot burns in patients with diabetes
Podiatry grand rounds.

Isolated subtalar arthrodesis vs. triple arthrodesis UTHSC-SA

Instructional course on interpretation of non-invasive vascular arterial studies and lower extremity angiograms
Post-graduate Diabetic Foot Course

Instructional hands-on course on foot amputations
Post-graduate Diabetic Foot Course

Interpretation of non-invasive arterial study as it relates to healing potential
Bandera Hill Country Seminar
Bandera, Texas

Imaging modalities of the diabetic foot
NPMA Conference
San Antonio, Texas

Footwear and insoles for diabetic patient workshop
Centers of Wound Healing Excellence: Improving Outcomes with New Technologies UTHSC-SA

1998

Surgical indications for Charcot’s arthropathy, Limb salvage in diabetic patients, Clinical application of non-invasive arterial studies.
Mid- Atlantic Podiatric Medical Association, West Virginia

2000

Diabetic workshop
Super Seminar 2000
Las Vegas, Nevada

Complicated wound panel
Western Podiatric Medical Congress
Anaheim, CA

Wound Care, The Multidisciplinary Approach
Essential of Practice Seminar
San Francisco, CA

2001
Diabetic workshop
Super Seminar 2001
Las Vegas, Nevada

Moderator for the Wound Care Track at the Super Seminar
Las Vegas, Nevada

Wound Bed Preparation
San Francisco, CA

Advances in Wound Care Technologies
Noon Conference Eden Hospital
Castro Valley CA

Diabetic Foot
Medicine Grand Rounds
California Pacific Medical Center
San Francisco CA

Bioengineered Skin Equivalents
Alameda County Podiatric Medical Association
San Leandro CA

Validation of Multidisciplinary Approach
Western Podiatric Medical Congress
Anaheim CA

Differential Diagnosis and Assessment of Lower Extremity ulcerations
Sutter Visiting Nurses
Vallejo, CA

Wound Bed Preparation
WOCN Association
Sacramento, CA

2002
Bioengineered Skin Equivalents: Dermagraft
SuperSeminar 2002
Las Vegas, NV

Lower Extremity Vascular Evaluation in a Diabetic Patient
Super Seminar 2002
Las Vegas, NV

Diabetic/Wound Care Workshop
Super Seminar 2002
Las Vegas, NV

Vacular Compromised Digit
Essentials of Practice 2002

Pathogenesis of Diabetic Foot Ulcerations
University of Texas Diabetic Foot Conference
San Antonio, TX 2002.

Diabetic Foot Infections
San Francisco and San Mateo County Podiatry Association, 2002

Diabetic Foot Infections
Santa Clara County Podiatry Association, 2002

2003
Diabetic Foot Infections
Alameda and Contra Costa County Podiatry Association, 2003

Approach to lower extremity ulcerations
Sutter Visiting Nurses Association, 2003

Diabetic Wound Care workshop
Super Seminar 2003
Las Vegas, NV

Advances in Wound Care. The Role of the VAC.
The Western Seminar 2003
Anaheim, CA

Management of the Diabetic Foot Ulcerations
Modesto and Stockton Podiatry Association
Stockton, CA 2003.

Diabetic Foot Infections
Sacramento Podiatry Association
Sacramento, CA 2003

2004
Diabetic Wound Care Track
Super Seminar 2004

The Role of the VAC
The Western 2004
Anaheim, CA

Diabetic Wound Care Update
Alameda Contra Costa Podiatry Association, CA

2005
Transmetatarsal Amputations
The Western 2005
Anaheim, CA

Patient Care and Research
The Western 2005
Anaheim, CA

Peripheral Neuropathy and Its Effects on the Lower Extremity
UCSF

Update on the use of Antibiotics in Treatment of Diabetic Foot Infections
San Francisco, CA

2007
Management of Diabetic Foot Infections
St. Mary’s Hospital Department of Podiatry
April 2007

Management of the Diabetic Foot
California Pacific Medical Center
Grand Rounds, June 2007

Treatment of Diabetic Foot Infections
Las Vegas, Nevada
August 2007

Treatment of Diabetic Foot Infections
University Medical Center
Grand Rounds
Las Vegas Nevada
November 2007

Management of Diabetic Foot Infections
UCSF Surgery Dept.
July 2007

Systemic Approach to Diabetic Foot Infections
Diabetic Foot Update Conference
University of Texas Health Science Center at San Antonio
December 2007

Teaching Points in Performing Foot Amputations
Diabetic Foot Update Conference
University of Texas Health Science Center at San Antonio
December 2007

2008
Common Foot Problems in the Emergency Department
Eden Hospital Emergency Department

Pathophysiology of the Diabetic Foot Ulcerations
Pacific Coast Region of the WOCN
Sacramento, CA

2009
Using Skin Expansion Device in Lower Extremity Wounds
1st Annual Wound Care Conference
Oakland, CA

Offloading Techniques in Treatment of Diabetic Foot Ulcerations.
Western Podiatric Congress
Anaheim, CA.

2010
Update on Treatment of Diabetic Foot Infections/MRSA.
2nd Annual Wound Care Conference
Oakland, CA

Chronic Wounds: What are They and What Makes Them Chronic.
2nd Annual Wound Care Conference
Oakland, CA.

Biological Dressings
2nd Annual Wound Care Conference
Oakland, CA.

Advanced Wound Healing Modalities
Western Congress
Disneyland, CA

2011
Heel Ulcers Management and Treatment
APWCA Conference
Philadelphia

Pathophysiology of Diabetic Foot
UCSF Vascular Grand Rounds, February 2011.

Diabetic Foot Ulcer Management and Prevention
UCSF Vascular Symposium
San Francisco, CA April 2011

Extreme Foot Salvage
UCSF Vascular Symposium
San Francisco, CA April 2011

Management of Heel Ulcers
Wound Care Conference
Oakland CA., May 2011.

NPWT, Wound Care Conference
Oakland, CA., May 2011.

Foot Salvage Options in Severe Diabetic Foot Infections
Anaheim, CA June 2011

2012
Long-term viability of Partial foot Amputations
UCSF Vascular Symposium
San Francisco, CA April 2012

Surgical Offloading: What is the Evidence?
UCSF Vascular Symposium
San Francisco, CA April 2012.

Biology of Wound Healing
Science Summit for Advanced Techniques in Wound Healing
Chicago, IL, July 2012

Assessment of Wound Complications and Management
Science Summit for Advanced Techniques in Wound Healing
Chicago, IL July 2012

2013
Heel Ulcers, Do They Have a Chance to Heal?
UCSF Vascular Symposium 2013

Management of Diabetic Foot Infections
Wound Care Conference
Oakland, CA May 2013

Treatment of Osteomyelitis, Surgical vs. Medical.
Western Podiatric Congress
Anaheim, CA June 2013.

When to Amputate and When to be Conservative?
IGOT International Summit: Trauma Wound Management & Flap course
San Francisco, September 2013

Use of Acellular Dermal Matrix in Chronic Wounds
SAWC
Las Vegas September 2013.

2014
Challenging Limb Salvage Cases: UCSF Vascular Symposium
San Francisco April 2015

Topical Compound Medication for Painful Diabetic Peripheral Neuropathy: Is it Snake Oil?
Wound Care Conference
Oakland, CA May 2014

2015
Biomechanical Evaluation of the Diabetic Foot
UCSF Vascular Symposium
SF April 2015

The Devil is in the Detail
UCSF Vascular Symposium
SF April 2015

Multidisciplinary Approach to Limb Salvage
Univ. Washington
Pacific Northwest Endovascular Conference May 2015.

Imaging of the Diabetic Foot
New Cardiovascular Horizons
New Orleans May 2015

Western Podiatric Congress
Anaheim, CA June 2015

IGOT International Summit
Trauma Wound Management & Flap course
San Francisco, September 2015

2016
Neurovascular Complication of Diabetes
UCSF Vascular Symposium
SF 2016

WiFi Classification
UCSF Vascular Symposium
SF 2016

2017
Timing and Type of Revascularization and its effect on Outcomes of Partial Foot Amputations
NCVH, New Orleans 2017

When is the Foot Worth Saving?
NCVH, New Orleans 2017

Usefulness of The MRI in Diagnosing Osteomyelitis
UCSF, Vascular Symposium
SF 2017

Leadership

2011-present
Co-Director, UCSF Center for Limb Preservation

2010 to Present
Associate Professor, Department of Medicine
California School of Podiatric Medicine at Samuel Merritt University

2009 to 2010
Associate Professor, Chair Department of Medicine
California School of Podiatric Medicine at Samuel Merritt University

2001 to 2009
Assistant Professor, Chair Department of Medicine
California School of Podiatric Medicine

2000 to 2001

Co-chair, Department of Medicine
California College of Podiatric Medicine
San Francisco, CA

2003 to Present

Board of Editorial Advisors for Podiatry Today

2000 to 2003

Editor of “Diabetes Watch” column
Podiatry Today journal

1997 to 1998

Administrative and academic chief resident
Department of Orthopaedics/Podiatry Service
University of Texas Health Science Center at San Antonio

1994 to 1995

President of Health and Honors Fraternity at the University of San Francisco

Research/Completed Clinical Trials

Primary Investigator for: An Open Label, Multicenter Study to Evaluate The Use of Dermagraft in Patients with Diabetic Foot Ulcers. (IDE), Advanced Tissue Sciences. Completed -12/2001.

Primary Investigator for: A Phase III, Prospective, Randomized, Comparative Study of Drug XXX to placebo in subjects with acute pain following bunionectomy surgery. Completed- 10/2000.

Primary Investigator for: “A Phase III, Prospective, Randomized, Stratified, Comparative Study of Next Generation Cover Dressing Versus Two Competitive Foam Dressings in the Management of Venous Leg Ulcers” Convatec. Completed-6/29/02.

Primary Investigator for: “A Phase IV Study of Aquacel Ag Dressing Versus Saline-Moistened Gauze in the Management of Diabetic Foot Ulcers” Completed 2004

Primary Investigator for: “A Comparative Prospective, Randomized Double-Masked, Parallel Group, Controlled Trial of Celleration Mist Therapy System (MTS) Versus Sham Control When Added to Standard of Care in the Treatment of Diabetic Neuropathic Ulcers”, Completed 2004

A Prospective, Randomized, Controlled, Multi-center Pivotal Trial of AutoloGel™ Versus Control When Added to the Standard of Care in the Treatment of Non-healing Diabetic Foot Ulcer, Completed 2005.

Primary Investigator for: “A Clinical Trial to Assess the Efficacy and Safety of Cefdinir for the Treatment of Uncomplicated Skin and Skin Structure Infections in The Diabetic Foot.” Completed 2005

Primary Investigator for: “A Randomized Controlled Multicenter Trial of Vacuum Assisted Closure Therapy in the Treatment and Blinded Evaluation of Venous Stasis Ulcers”

Primary Investigator for: “A Trial Comparing topical antifungal agents in the treatment of tinea pedis.”

Primary Investigator for “A Confirmatory Study to Evaluate The Safety and Efficacy of Cryopreserved Bilayered Cellular Matrix (Orcel) For the Treatment of Venous Ulcers”

Primary Investigator for: “A Phase 3, Randomized, Double-Blind, Multinational Trial of Intravenous Telavancin Versus Vancomycin for Treatment of Complicated Gram-Positive Skin and Skin Structure Infections with a Focus on Patients with Infections Due to Methicillin-Resistant Staphylococcus Aureus.

Primary Investigator for: “Linezolid in the Treatment of Subjects with Complicated Skin and Soft Tissue Infections Proven To Be Due to Methicillin-Resistant Staphylococcus Aureus”

A Prospective Randomized Trial in the Treatment of Subjects with Onychomycosis.

Primary Investigator for “A Multi-Center, Double-Blind, Randomized Study Assessing the Efficacy of a drug for Diabetic Peripheral Neuropathy.

KCI VAC Protocol VAC2001-08, “A Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy in the Treatment and Blinded Evaluation of Diabetic Foot Ulcer”.

Primary Investigator for “A Multi-Center, comparator trial, comparing two different compression bandage systems for venous leg ulcers”. 3M Corporation

A Randomized, Blinded-Assessor, Controlled Study of NVC-101 in the Treatment of Chronic Non-Healing Venous Stasis Ulcers.

A Multicenter, randomized study of the safety and preliminary efficacy of topical low-dose nicotine gell (XXX) in patients with plantar diabetic foot ulcers

Primary Investigator for “A Multi-Center, Double-Blind, Randomized, Parallel, Vehicle-Controlled Dose-Ranging Study Assessing the Safety and Efficacy of (XXX) Gel Versus Matching Vehicle Gel When Applied Topically for Three Months to Subjects with Diabetic, Neuropathic, Foot Ulcers”

“Pivotal Study to Evaluate the Efficacy and Safety of Dermal-Living Skin Replacement (XXX) in the Treatment of Chronic Diabetic Foot Ulcers XXX-2004”.

A Prospective, Randomized, Comparative Parallel Study of Acellular Matrix Wound Dressing In the Management of Diabetic Foot Ulcers

A Prospective, Multi-Centre, Double Blind Randomized Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of (XXX) in a Phase III Trial with Four-Layer Therapeutic Compression, For the Treatment of Non-Infected Skin Leg Ulcers, Due to Venous-Insufficiency”

A Prospective, Multi-Center, Open-Label Study to Evaluate the Safety and Effectiveness of Healadex Wound Dressing in the Treatment of Chronic Ulcers of the Lower Extremities, Protocol #XXX

A Double-Blind, Randomized, Parallel-Group, Vehicle-Controlled, Multi-Center Study to Evaluate the Safety and Clinical Equivalence of a Generic Ciclopirox Gel 0.77% to Loprox® Gel (Ciclopirox) 0.77% in the Treatment of Interdigital Tinea Pedis

A Multicenter, randomized, double-blind, comparison study of the safety and efficacy of a once-daily dose of tigecycline versus Ertapenem for the treatment of foot infections in subjects with diabetes.

A Randomized, Controlled, Open-Label Study to Investigate the Safety and Efficacy of a Topical XXX (XXX) in Combination with Antimicrobial Therapy Compared to Antimicrobial Therapy Alone in Diabetic Patients with Moderately Infected Lower Extremity Skin Ulcers”.

A Randomized, Double-Blind, Vehicle-controlled, Parallel Group, Dose-Ranging, Multi-center Study of the Efficacy and Safety of XXX in the Treatment of Participants with Venous Leg Ulcers

Use of the dermaPACE™ (Pulsed Acoustic Cellular Expression) Device in Conjunction with Standard of Care in the Treatment of Diabetic Foot Ulcers”

Evaluation of a Medical Food for Chronic Wounds of the Lower Extremity in Patients with Diabetes. Multicenter trial.

A Phase III, Multinational Multicenter, Randomized, Double-blind, Parallel-Group, Sham-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of XXX as an Adjunct to Good Wound Care Measures in Treating Lower Extremity Chronic Ulcers in Adults with Diabetes Mellitus.

Lower Extremity Venous and Diabetic Ulcer Negative Pressure Wound Therapy Trial. Comparing KCI wound VAC to Spiracur SNaP device.
A Phase II Randomized, Double Blind, Placebo Controlled Dose Finding Study Investigating the Efficacy of (XXX) in Venous Leg Ulcers
A Phase II, Controlled, Two-Center Pilot Study of the Safety and Efficacy of Topically Applied XXX Wound Ointment Compared to Standard of Care in Subjects with Venous Ulcers”

A Multi-centered, Prospective, Randomized, Double-blind Comparison
of 3M™ XXX Dressing technology to a Placebo Dressing in the Management of Non-healing Diabetic Foot Ulcers

A Randomized, Parallel Group, Dose-Ranging, Controlled, Multi-center Study to Assess the Efficacy and Safety of XXX in the Treatment of Subjects with Venous Leg Ulcers”

“A Prospective, Randomized, Controlled, Unmasked, Multiple Treatment, Multi-Center Clinical Trial to Evaluate the Efficacy and Safety of an Interactive Wound Dressing containing (XXX) versus Conventional Wound Therapy for the Treatment of Diabetic Foot Ulcers.

A Phase 3, Multicenter, Randomized, Double-Blind Study Evaluating the Safety and Efficacy of XXX Topical Solution versus Vehicle in Subjects with Mild to Moderate Onychomycosis of the Toenails

A Phase II, Controlled, Two-Center Pilot Study of the Safety and Efficacy of Topically Applied XXX Wound Ointment Compared to Standard of Care in Subjects with Diabetic Foot Ulcers”

A Randomized, Double-Blind, Vehicle-Controlled, Multi-Center Study to Evaluate the Efficacy and Safety of XXX Topical Solution, 5%, vs. Solution Vehicle in the Treatment of Onychomycosis of the Toenail in Adults

Prospective, Randomized, Multiple Site Clinical Trial Comparing the Effectiveness of Novel Pressure Based Insoles to Current Care for Ulcer Prevention.

Safety and Efficacy of XXX 10ug in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers.

A Randomized, Controlled, Multi-Center Trial to Assess Safety and Efficacy of XXX in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers”

A Phase III, Multinational, Multicenter, Randomized, Double-Blind, Parallel-Group, Sham-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of XXX as an Adjunct to Good Wound Care Measures in Treating Lower Extremity Chronic Ulcers in Adults with Diabetes Mellitus.

A Phase 3 Randomized, Double Blind, Vehicle Controlled Study Investigating the Safety and efficacy of XXX in the Treatment of Venous Leg Ulcers.

An Outcome Study Evaluating the Effectiveness of DermaTranRx in the Treatment of Chronic Neuropathic Pain.

Multi-Center, Randomized, Controlled Clinical Trial to Evaluate The Safety and Effectiveness of Integra Dermal Regeneration Template for the Treatment of Neuropathic Diabetic Foot Ulcers.

In-home assessment of Smart Foot Mat for Prevention of Diabetic Foot Ulcers.

An Evaluation of Tissue Engineering Approaches for Treatment of Neuropathic Diabetic Foot Ulcers Resistant to Standard of Care: A Prospective, Randomized controlled Trial.

A Phase 2 Randomized, Double-Blind, Vehicle-Controlled, Dose-Ranging Study to Investigate the Efficacy and Safety of XXX in Patients with Mild to Moderate Onychomycosis

A Phase-3 Prospective, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of XXX as an Adjunct to Good Ulcer Care Measures in Treating Chronic Venous Leg Ulcers

Clinical Outcomes Associated with Enzymatic Debridement of Diabetic Foot Ulcers for up to 12 weeks with XXX Ointment

Randomized, Parallel-Group, double-Blind, Vehicle-Controlled Phase III Clinical Trial to Evaluate the Effectiveness of DSC127 in Treating Non-Healing Diabetic Foot Ulcers (DFU).

Open-Label Phase III Clinical Trial to Evaluate the Safety of 0.0X% XXX Gel in Chronic Use for Treating Diabetic Foot Ulcers (DFU)

A Phase2, Randomized, Double Blind, Placebo-Controlled, Dose- Ranging Study to Evaluate the Efficacy and Safety of XXX Oral Tablets in the Treatment of Patients with Distal and Lateral Subungual Onychomycosis of the Toenail

A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose Range finding Study to Evaluate the Efficacy and Safety of Intramuscular Injection of Human Placenta-Derived Cells (XXX) in Subjects who have Diabetic Foot Ulcer with Peripheral Arterial Disease

Phase I Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Topical XXX in Healthy Volunteers and Diabetic Patients and Repeat Doses XXX in Diabetic Patients for the Treatment of Diabetic Foot Ulcer.

A Phase IIb, Prospective, Single-Blinded, Randomized Controlled Trial of the Micronized XXX Injection as Compared to Saline Placebo Injection In the Treatment of Plantar Fasciitis

A Multicenter Prospective, Randomized, Controlled, Comparative Parallel Study of XXX Wound Graft in the Management of Diabetic Foot Ulcer

A Multicenter, Randomized, Single-blind Study with an Open-Label Extension Option to Further Evaluate the Safety and Efficacy of Cryopreserved Human Amniotic Membrane for the Treatment of Chronic Diabetic Foot Ulcers.

A Multicenter, Prospective, Randomized, Parallel-group, Standard of Care-controlled Clinical Trial to Evaluate the Use of XXX in the Management of Chronic Diabetic Foot Ulcers

Clinical Trials in Progress

A Prospective, Randomized, Comparative Effectiveness Study of a Single-use, Negative Pressure Wound Therapy System (XXX) versus a Traditional Negative Pressure Wound Therapy System (XXX) in the Treatment of Lower Extremity Ulcers

A Randomized, Double-Blind, Multicenter, Superiority, Placebo-Controlled Phase 3 Study of XXX Cream 0.X% Applied Twice Daily for 14 days in the Treatment of Adults with Mild Infections of Diabetic Foot Ulcers

A Randomized, Prospective, Multi-center Feasibility Study of APT 001 Plasma/Nitric Oxide Therapy for the Treatment of Diabetic Foot Ulcers

A Phase 1b, Blinded, Randomized, Multicenter, Ascending-dose study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UTTR1147A Administered by Subcutaneous Injection in Patients with Non-Healing Neuropathic Diabetic Foot Ulcers.

MOB015B-IV, A Multi-centre, double blind, randomized, vehicle controlled study of efficacy and safety of topical MOB015B in the treatment of mild to moderate distal sublingual onychomycosis (DSO)

A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of VM202 to Treat Chronic Non-healing Foot Ulcers in Diabetic Patients with Concomitant Peripheral Arterial Disease (PAD)

A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of VM202 in Subjects with Painful Diabetic Peripheral Neuropathy.

Consulting

Medicis Laboratories

Podiatry Advisory Panel

2002

Eli Lilly

Neuropathy Advisory Panel

2004

Wound Care Technologies Inc.

2008 to Present

Aalnex Inc.

2008 to Present

Publications

Day, R.D., Reyzelman, A., Harkless, L.B., Evaluation and Management of the Interdigital Corn: A Literature Review. Clin Pod Med Surg 13:2, April, 1996.

Reyzelman, A.M., Van Gils, C, Hardin, T.C., Vayser, D.J., Harkless, L.B.,Vancomycin-resistant Enterococci (VRE) Osteomyelitis in the Foot: A Case Report. J. Am. Pod. Med. Assoc. 87:9, September 1997.

Felder-Johnson, K.L., Reyzelman, A.M. “Foot and Ankle Trauma”, Foot and Ankle Secrets, 1st Ed. Hanley & Belfus, Philadelphia, PA 1998.

Reyzelman, A.M., Lomba, M.R., Vayser, D.J., Day, R.D., Burnett, O.E., Central Pain Syndrome with Manifestations in the Foot: A Case Report and Literature Review. J. Amer. Pod. Med. Assoc. 88:5, May 1998.

Reyzelman, A.M., Armstrong, D.G., Hadi, S.A., Vayser, D.J., Husain, S.K., Harkless, L.B., Emergence of Non-Group A Streptococcal Necrotizing Diabetic Foot Infections. J. Amer. Pod. Med. Assoc. 88:6, June 1998.

Morgan, C.B., Reyzelman, A.M., Cai, T.H., Harkless, L.B., Pre-operative Assessment of Transplant Patient: J Foot & Ankle Surgery. 37:4, July/August 1998.

Reyzelman, A.M., Hadi, S.; Armstrong, D.G., Limb Salvage with Chopart’s Amputation and Tendon Balancing: J. Amer. Pod. Med. Assoc. 89:2, February 1999.

Reyzelman, A.M., Lipsky, BA., Hadi, S., Harkless, L.B., Armstrong DG. The Increased Prevalence of Severe Necrotizing Infections Caused by Non-Group A Streptococci. J. Amer. Pod. Med. Assoc. 89:9, September 1999

Steinberg, J.S., Reyzelman, A.M.: The Diabetic Foot:A Multidisciplinary Team Approach. Podiatry Today 1999

Reyzelman, A.R., Tuthill, J.: Management of Diabetic Wounds and Infections, Home Health Care Consultant, 7:4 April 2000.

Reyzelman, A.R., Loveland, L.J., Melillo, T.C.: Tendon Rebalancing Improves Chopart Outcomes. Biomechanics, May 2000.

Loveland, L.J., Reyzelman, A.M.: Why Tendon Balancing is Essential For Amputation of The High-Risk Diabetic Foot. Podiatry Today, May 2000

Reyzelman, A.M., Trombello, K.A., Vayser, D.J., Armstrong, D.G., Harkless, L. B.: Are Antibiotics Necessary in the Treatment of Locally Infected Ingrown Toenails? Arch. Fam. Med. 9:Sept/Oct. 2000.

Jansma, J., Van Voris, K., Reyzelman, A.M: Management of Diabetic Wounds and Infections in the Elderly Patient. Clinical Geriatrics. 9:7, June 2001

La Fontaine, J., Reyzelman A.M., Rothenberg, G., Husain, K., Harkless, L.B.: The Role of Revascularization in Transmetatarsal Amputations: J. Am. Pod. Assoc. 91:10, November/December 2001

Reyzelman, A., Tidwell, A.: Expert’s Tips on Wound Bed Preparation: Podiatry Today July 2003.

Reyzelman, A.: Bracing and Orthotics. Guest Editor. Foot and Ankle Quarterly The Seminar Journal. Vol 16:4 Winter 2004.

Reyzelman, A.: Current Trends in Performing Matrixectomies
Podiatry Today, December 2005.

Reyzelman, A., Fiorito, J., Hoover, C., Brewer, M.: Key Insights on Lower Extremity Nerve Testing, Podiatry Today, October 2007

Moffatt, C.J., Edwards, M.C., Treadwell, T., Miller, M., Shafer, L., Sibbald, G., Brassard, A., McIntosh, A., Reyzelman, A., Price, P., Merkel, K., Walters, S., Harding, K.A. A randomized controlled 8 week crossover clinical evaluation of the 3M Coban 2 Layer Compression System versus Profore to evaluate the product performance in patients with venous leg ulcers., Int Wound J 2008;5:267-279.

Reyzelman AR, Crews RT, Moore JC, Moore L, Mukker JS, Offutt S, Tallis
A, Turner WB, Vayser D, Winters C, Armstrong DG, “Clinical Effectiveness
of an Acellular Dermal Regenerative Tissue Matrix Compared to Standard
Wound Management in Healing Diabetic Foot Ulcers: A Prospective,
Randomized, Multi-Center Study, Int. Wound Journal, 2009,

Wilson, D.J., Fullen, J.G., Reyzelman, A.M; Biomechanics of Foot Ulcer Rehabilitation and an In-Shoe-Based Clinical Prevention Methodology. Critical Reviews in Physical and Rehabilitation Medicine, 22 (1-4), 29-48 (2010).

Armstrong DG, Marston WA, Reyzelman AM, Kirsner RS, “Comparison of negative pressure wound therapy with an ultraportable mechanically powered device vs. traditional electrically powered device for the treatment of chronic lower extremity ulcers: A multicenter randomized-controlled trial. Wound Rep Reg (2011) 19 173-180.

Reyzelman A., Vayser D., Tam S.W., Dove C., “Initial Clinical Assessment of a Novel Wound Management System” A Case Series. Adv. Skin & Wound Care (2011) 24:6 256-260.

Balingit P., Armstrong D.G, Reyzelman A., Bolton L., Verco S., Rodgers K., Nigh K., diZerega G., NorLeu3-A(1–7) stimulation of diabetic foot ulcer healing: Results of a randomized, parallel-group, double-blind, placebo-controlled phase 2 clinical trial. Wound Rep Reg (2012) June.

Reyzelman A.M., Bazarov I., Can Traditional Herbal Medicine Help Heal Chronic Diabetic Foot Ulcers? Podiatry Today. June 2012.

Reyzelman, A.M., Bazarov I., Acellular Dermal Matrices (AMDs) in Treatment of Chronic Lower Wounds. Podiatry Management June/July 2012.

Lipsky, B.A., Kuss, M., Edmonds, M., Reyzelman, A., Sigal, F., Topical Application of a Gentamycin-Collagen Sponge Combined with Systemic Antibiotics Therapy for the Treatment of Diabetic Foot Infections of Moderate Severity, A Randomized, Controlled, Multicenter Clinical Trial, JAPMA Vol 102 (3) May/June 2012

Marston, W.A., Armstrong, D.G., Reyzelman, A.M., Kirsner, R.S., A Multicenter Randomized Controlled Trial Comparing Treatment of Venous Leg Ulcers Using Mechanically Versus Electrically Powered Negative Pressure Wound Therapy. Adv in Wound Care 2014.

Vartanian, S.M., Robinson, K.D., Ofili, K., Eichler, C.M., Hiramoto, J.S., Reyzelman, A.M., Conte, M.S., Outcomes of Neuroischemic Wounds Treated by a Multidisciplinary Amputation Prevention Service. Ann Vasc Surg 2015:29:534-542.

Reyzelman, A.M., Vartivarian, M., Evidence of Intensive Autolytic Debridement With a Self-Adaptive Wound Dressing, Case Series.. Wounds 2015;27(8):180-190.

Snyder RJ., Shimozaki K., Tallis A., Kerzner M., Reyzelman A., Lintzeris D., Bell B., Rutan R., Rosenblum B. A Prospective, Randomized Multicenter, Controlled Evaluation of the Use of Dehydrated Amniotic Memberane Allograft Compared to Standard of Care for the Closure of Chronic Diabetic Foot Ulcers. Wounds: 2016; 28(3):70-77

Walters J., Cazzell S., Pham H., Vayser D., Reyzelman A. Healing rates in a Multi-center Assessment of a Sterile, Room Temperature, Acellular Dermal Matrix vs. Conventional Care Wound Management and an Active Comparator in the Treatment of Full-thickness Diabetic Foot Ulcers. ePlasty: 2016;16:e10

Shih CD., Bazarov I., Harrington T., Vartivarian M., Reyzelman AM. Report on the Use of In-Office Cone Beam Computed Tomography for Early Diagnosis of Osteomyelitis in Diabetic Patients. JAPMA 2016:106(2) 128-132.

Causey MW., Ahmed A., Wu B., Gasper WJ., Reyzelman A., Vartanian SM., Hiramoto JS., Conte MS. Society for Vascular Surgery Limb Stage and Patient Risk Correlate with Outcomes in an Amputation Prevention Program. JVS 2016

Frykberg RG., Gordon IL., Reyzelman AM., Cazzell SM., Fitzgerald RH., Rothenberg GM., Bloom JD., Peterson BJ., Linders DR., Nouvong A., Najaf B. Feasibility and Efficacy of a Smart Mat Technology to Predict Development of Diabetic Plantar Ulcers. Diabetes Care 2017

Poster Presentations

Clinical Effectiveness of an Acellular Dermal Regenerative Tissue Matrix Compared to Standard Wound Management in Healing Diabetic Foot Ulcers: A Prospective, Randomized, Multi-Center Study. Presented at DFCON, Los Angeles, CA 3/2009.

Continuous External Tissue Expander For Closure of Lower Extremity Wounds. A Case Series. Presented at DFCON, Los Angeles, CA, 3/2009,
ACFAS 2009 and SAWC 2009.

A Novel Ultraportable Negative Pressure System in the Podiatrist Office Setting. Presented at DFCON, Los Angeles, CA 4/2011

Randomized Trial: Novel Angiotensin Analogue Effects on Diabetic Foot Ulcer healing; Presented at DFCON, Los Angeles, CA 4/2011

Effect of an Oral Nutritional Supplement on Wound Healing in High Risk Diabetic Patients. Presented at DFCON, Los Angeles, CA 3/2012.

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Four Oral Dosing Regimens of VT-1161 in the Treatment of Patients with Moderate-Severe Toenail Onychomycosis (RENOVATE): Results of a Planned Week 24 Interim Analysis. Presented at APMA in Philadelphia June 2016.

Efficacy and Safety of VT-1161 in a Randomized, Double-Blind, Placebo-Controlled Study of Four Oral VT-1161 Regimens in the Treatment of Patients with Moderate-to-Severe Distal-Lateral Subungual Onychomycosis (DLSO)
Presented at APMA in Nashville 2017.